Italy are expected to use Federico Bernardeschi as a False 9 with Lorenzo Insigne and Federico Chiesa in the friendly against Ukraine.
It kicks off at the Stadio Luigi Ferraris in Genoa on Wednesday at 19.45 UK time (18.45 GMT).
According to the latest reports, Roberto Mancini will retain his 4-3-3 formation even after losing Simone Zaza and Patrick Cutrone to injury.
As there is a Nations League match coming up against Poland next week, Lazio striker Ciro Immobile is likely to be kept on ice.
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